Figure 3: PM10-induced IL-1β release dependent on caspase-1 activation in THP-1-derived macrophages cells. The cells were pretreated with the caspase-1 inhibitor, z-YVAD-fmk (10 μM) for 1 h, and exposed to summer PM10 for 6 h. Results are the mean and s.d. of three independent experiments. CTRL: untreated cells. versus CTRL, versus summer PM10.