BioMed Research International / 2013 / Article / Fig 3

Research Article

Release of IL-1β Triggered by Milan Summer PM10: Molecular Pathways Involved in the Cytokine Release

Figure 3

PM10-induced IL-1β release dependent on caspase-1 activation in THP-1-derived macrophages cells. The cells were pretreated with the caspase-1 inhibitor, z-YVAD-fmk (10 μM) for 1 h, and exposed to summer PM10 for 6 h. Results are the mean and s.d. of three independent experiments. CTRL: untreated cells. versus CTRL, versus summer PM10.

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