Chronic Heat Stress Inhibits Immune Responses to H5N1 Vaccination through Regulating CD4<sup><b>+</b></sup>CD25<sup><b>+</b></sup>Foxp3<sup><b>+</b></sup> Tregs

<div class="floats-full-page floats-full-page-figure"><h2>Figure 5</h2><div class="floats-full-page-caption"><table>Adoptive transfer of CD4<sup>+</sup>CD25<sup>+</sup> Tregs reduces the vaccine efficacy under TN conditions. 10<sup>6</sup> CD4<sup>+</sup>CD25<sup>+</sup> Tregs from CHS+Ag group and TN+Ag group were adoptively transferred into TN+Ag mice on day 21 in conjunction with a 50 PFU H5N1 virus challenge. The mortalities of the two transferred groups (<svg height="11.225" id="M33" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,10.963)"><path d="M495 86q-46 -47 -87 -72.5t-63 -25.5q-43 0 -16 107l49 210q7 34 8 50.5t-3 21t-13 4.5q-35 0 -109.5 -72.5t-115.5 -140.5q-21 -75 -38 -159q-50 -10 -76 -21l-6 8l84 340q8 35 -4 35q-17 0 -67 -46l-15 26q44 44 85.5 70.5t64.5 26.5q35 0 10 -103l-24 -98h2&#10;q42 56 97 103.5t96 71.5q46 26 74 26q9 0 16 -2.5t14 -11.5t9.5 -24.5t-1 -44t-13.5 -68.5q-30 -117 -47 -200q-4 -19 -3.5 -25t6.5 -6q21 0 70 48z" id="x1D45B"></path></g><g transform="matrix(.017,-0,0,-.017,13.305,10.963)"><path d="M535 323h-483v50h483v-50zM535 138h-483v50h483v-50z" id="x3D"></path></g><g transform="matrix(.017,-0,0,-.017,28.008,10.963)"><path d="M137 343l67 33q37 17 63 17q79 0 129.5 -53t50.5 -131q0 -92 -58 -156.5t-147 -64.5t-147 68t-58 182q0 63 17 119t43 95.5t61.5 72t69 52t67.5 31.5q62 22 128 33l6 -32q-56 -11 -108 -35q-149 -71 -184 -231zM227 337q-47 0 -95 -27q-6 -23 -6 -70q0 -93 36 -155.5&#10;t96 -62.5q53 0 78 45.5t25 105.5q0 68 -35 116t-99 48z" id="x36"></path></g>
</svg>) were observed for 14 days.</table></div><div class="floats-full-page-content"><table class="table-group" width="800px"><tr class="fig-image" id="a"><td><img alt="160859.fig.005a" src="https://static-01.hindawi.com/articles/bmri/volume-2013/160859/figures/160859.fig.005a.jpg" /></td></tr><tr class="fig-caption"><td align="center"><table><tr><td><b>(a) </b></td></tr></table></td></tr><tr class="fig-image" id="b"><td><img alt="160859.fig.005b" src="https://static-01.hindawi.com/articles/bmri/volume-2013/160859/figures/160859.fig.005b.jpg" /></td></tr><tr class="fig-caption"><td align="center"><table><tr><td><b>(b) </b></td></tr></table></td></tr></table></div></div>

Figure 5 | Chronic Heat Stress Inhibits Immune Responses to H5N1 Vaccination through Regulating CD4<sup><b>+</b></sup>CD25<sup><b>+</b></sup>Foxp3<sup><b>+</b></sup> Tregs

title

Figure 5: Chronic Heat Stress Inhibits Immune Responses to H5N1 Vaccination through Regulating CD4<sup><b>+</b></sup>CD25<sup><b>+</b></sup>Foxp3<sup><b>+</b></sup> Tregs

description

Figure 5 | Chronic Heat Stress Inhibits Immune Responses to H5N1 Vaccination through Regulating CD4+CD25+Foxp3+ Tregs

Figure 5

About this journal

<p><em>BioMed Research International</em> publishes original research articles, review articles, and clinical studies covering a wide range of subjects within the biomedical sciences. The journal will accept both basic and translational research.</p>


Journal profile

Meet the editorial board

<p><em>BioMed Research International</em> maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.</p>


Editor spotlight

Submit to Special Issue

We currently have a number of Special Issues open for submission. Special Issues highlight emerging areas of research within a field, or provide a venue for a deeper investigation into an existing research area.