Biomedical Applications of Fermenticin HV6b Isolated from Lactobacillus fermentum HV6b MTCC10770

Table 2

Cytotoxic effect of fermenticin on cancerous cells.

Cancer cell lines tested	% cell viability at bacteriocin concentration			IC-50 value (𝜇g/mL)
	0.1 𝜇g/mL	1 𝜇g/mL	10 𝜇g/mL
MCF-7	88±1.9	46±2.1	10±1.7	0.9±0.016
Sp2/0	70±1.4	30±1.7	9±1.5	0.5±0.012
Hep-G2	50±1.8	20±1.5	10±1.9	0.1±0.014
HEK-293	78±2.4	38±2.8	8±2.6	0.6±0.015
HeLa	65±1.3	25±1.2	6±1.6	0.4±0.013

Each data is mean ± standard deviation; 𝑃 value < 0.05; 𝐹 crit (3.2388) < 𝐹 value (62.3008).