New Morphological Features for Grading Pancreatic Ductal Adenocarcinomas

<table> (a) A set of the segmented nuclei, <svg height="12.3625" id="M19" style="vertical-align:-0.28665pt" version="1.1" viewbox="0 0 18.737499 12.3625" width="18.737499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.95)"><path d="M695 175h4q47 62 85 165q14 40 26 80l30 92q33 98 77 144q40 43 89 43q33 0 52.5 -20t19.5 -48t-19.5 -47.5t-46.5 -19.5q-43 0 -64 39h-4q-19 -16 -37 -65l-42 -128q-25 -80 -48 -135q-37 -84 -93 -163q-57 -81 -116 -125h-51q10 62 11 105l3 57q0 7 0.5 17t1 26t0.5 29
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</svg>; (b) a set of the epithelial nuclei selected from <svg height="12.3625" id="M20" style="vertical-align:-0.28665pt" version="1.1" viewbox="0 0 18.737499 12.3625" width="18.737499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.95)"><path d="M695 175h4q47 62 85 165q14 40 26 80l30 92q33 98 77 144q40 43 89 43q33 0 52.5 -20t19.5 -48t-19.5 -47.5t-46.5 -19.5q-43 0 -64 39h-4q-19 -16 -37 -65l-42 -128q-25 -80 -48 -135q-37 -84 -93 -163q-57 -81 -116 -125h-51q10 62 11 105l3 57q0 7 0.5 17t1 26t0.5 29
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</svg><i>,  </i><svg height="16.9625" id="M21" style="vertical-align:-0.28665pt" version="1.1" viewbox="0 0 29.1875 16.9625" width="29.1875" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,16.537)"><path d="M695 175h4q47 62 85 165q14 40 26 80l30 92q33 98 77 144q40 43 89 43q33 0 52.5 -20t19.5 -48t-19.5 -47.5t-46.5 -19.5q-43 0 -64 39h-4q-19 -16 -37 -65l-42 -128q-25 -80 -48 -135q-37 -84 -93 -163q-57 -81 -116 -125h-51q10 62 11 105l3 57q0 7 0.5 17t1 26t0.5 29
t0.5 39.5t1.5 36.5q5 121 28 215h-2q-43 -67 -100 -183q-108 -220 -171 -284q-63 -66 -138 -66q-58 0 -95 33t-37 86q0 35 25.5 62.5t60.5 27.5q32 0 51.5 -20.5t19.5 -50.5q0 -23 -19 -42.5t-47 -19.5v-1q11 -20 48 -20q55 0 109 72t137 236q51 103 95 179q39 65 78 105
q36 38 101 68l25 -22q-8 -20 -12 -55q-6 -49 -7 -65l-6 -89l-6 -88q-11 -157 -18 -200z" id="x1D4DD"></path></g>
<g transform="matrix(.012,-0,0,-.012,18.675,8.375)"><path d="M414 683l-14 -48q-30 9 -77 9q-62 0 -99.5 -26t-37.5 -69q0 -86 148 -96q15 92 119 163t208 71q130 0 130 -80q0 -65 -99 -129q-100 -65 -241 -80v-3q80 -11 80 -37q0 -18 -19 -30q-17 -12 -53 -11.5t-63 14.5q-72 -25 -114.5 -78.5t-42.5 -117.5q0 -45 31 -73t83 -28
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</svg> (marked as red).</table>

BioMed Research International

fig4

Figure 4

Figure 4: New Morphological Features for Grading Pancreatic Ductal Adenocarcinomas 