New Morphological Features for Grading Pancreatic Ductal Adenocarcinomas

Table 14

LSD test for F-test of lumen features.

Lumen features	LSD test
	|𝑁−𝐺1|	|𝑁−𝐺2|	|𝐺1−𝐺2|	LSD value
Area (μm^2)	𝟐.𝟗𝟗𝐄+𝟎𝟒^∗	𝟖.𝟏𝟒𝐄+𝟎𝟒^∗	𝟓.𝟏𝟓𝐄+𝟎𝟒^∗	𝟐.𝟑𝟗𝐄+𝟎𝟒
Perimeter (μm)	𝟔.𝟎𝟏𝐄+𝟎𝟐^∗	𝟏.𝟐𝟓𝐄+𝟎𝟑^∗	𝟔.𝟒𝟔𝐄+𝟎𝟐^∗	𝟐.𝟗𝟓𝐄+𝟎𝟐
Width (μm)	𝟖.𝟔𝟗𝐄+𝟎𝟏^∗	𝟏.𝟖𝟎𝐄+𝟎𝟐^∗	𝟗.𝟐𝟕𝐄+𝟎𝟏^∗	𝟒.𝟗𝟑𝐄+𝟎𝟏
Height (μm)	𝟔.𝟎𝟓𝐄+𝟎𝟏^∗	𝟏.𝟐𝟔𝐄+𝟎𝟐^∗	𝟔.𝟓𝟔𝐄+𝟎𝟏^∗	𝟑.𝟑𝟐𝐄+𝟎𝟏
MajorAxis (μm)	𝟏.𝟎𝟕𝐄+𝟎𝟐^∗	𝟐.𝟎𝟖𝐄+𝟎𝟐^∗	𝟏.𝟎𝟏𝐄+𝟎𝟐^∗	𝟓.𝟑𝟒𝐄+𝟎𝟏
MinorAxis (μm)	𝟓.𝟗𝟏𝐄+𝟎𝟏^∗	𝟏.𝟑𝟕𝐄+𝟎𝟐^∗	𝟕.𝟖𝟎𝐄+𝟎𝟏^∗	𝟑.𝟑𝟒𝐄+𝟎𝟏
Circularity	3.90𝐸−03^∗	3.18𝐸−03^∗	7.25𝐸−04	3.13𝐸−03
Feret’s diameter (μm)	𝟐.𝟐𝟐𝐄+𝟎𝟐^∗	𝟒.𝟓𝟒𝐄+𝟎𝟐^∗	𝟐.𝟑𝟐𝐄+𝟎𝟐^∗	𝟏.𝟎𝟗𝐄+𝟎𝟐
Skewness	𝟗.𝟒𝟏𝐄−𝟎𝟏^∗	𝟏.𝟐𝟎𝐄+𝟎𝟎^∗	𝟐.𝟔𝟏𝐄−𝟎𝟏^∗	𝟐.𝟒𝟖𝐄−𝟎𝟏
AspectRatio	1.63𝐸−01^∗	1.34𝐸−01	2.90𝐸−02	1.34𝐸−01
Roundness	—	—	—	—
Solidity	—	—	—	—
AtypiaRatio	𝟐.𝟐𝟏𝐄−𝟎𝟏^∗	𝟒.𝟏𝟕𝐄−𝟎𝟏^∗	𝟏.𝟗𝟕𝐄−𝟎𝟏^∗	𝟕.𝟗𝟗𝐄−𝟎𝟐
#AtypiaRegions	𝟐.𝟒𝟎𝐄+𝟎𝟎^∗	𝟒.𝟕𝟔𝐄+𝟎𝟎^∗	𝟐.𝟑𝟔𝐄+𝟎𝟎^∗	𝟔.𝟗𝟎𝐄−𝟎𝟏
RMSAA	𝟕.𝟖𝟐𝐄+𝟎𝟎^∗	𝟏.𝟕𝟕𝐄+𝟎𝟏^∗	𝟗.𝟗𝟐𝐄+𝟎𝟎^∗	𝟑.𝟕𝟕𝐄+𝟎𝟎
TSAV (rad)	𝟖.𝟒𝟓𝐄+𝟎𝟑^∗	𝟐.𝟓𝟗𝐄+𝟎𝟒^∗	𝟏.𝟕𝟒𝐄+𝟎𝟒^∗	𝟓.𝟖𝟖𝐄+𝟎𝟑

∗It indicates that the absolute pairwise difference is greater than LSD value.