BioMed Research International / 2013 / Article / Tab 3

Research Article

Downregulation of DLC-1 Gene by Promoter Methylation during Primary Colorectal Cancer Progression

Table 3

Methylation status, pathological features, and molecular alternations in CRCs and adenomas.

 CRCsAdenomas
 Non methylationPartial methylationExtensive methylation valueNon methylationPartial methylationExtensive methylation value

Age (y)
 <60144150.0988830.397
 ≥6018151423105
Gender
 Female1411200.139131140.433
 Male18891874
Location
 Distal1715160.151231560.829
 Proximal15413832
Dukes’ stage
 A + B23770.004
 C458
 D5714
Differentiation
 Well and moderately199110.259
 Poorly131018
Size
 <1 cm147130.8814620.598
 ≥1 cm18121617126
KRAS mutation status
 Wild-type2413110.01261470.889  
 Mutation8618541

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