Safety Assessment and Biological Effects of a New Cold Processed SilEmulsion for Dermatological Purpose

Table 4

Physical and chemical properties of the ingredients presented in the SilEmulsion.

INCI name	CAS number	Molecular weight (g/mol)	Impurities	Log 𝑃ow^∗
Aqua	7732-18-5	18.02	n.a.	—
Bis-PEG/PPG-16/16 PEG/PPG-16/16 dimethicone (and) caprylic/capric triglyceride	n.a.	>10000 [10]	n.a.	n.a.
PEG-20 glyceryl laurate	59070-56-3	362.50 [11]	Ethyleneoxide <1 ppm; Dioxane <5 ppm	3.70 [11]
Isopropyl myristate	110-27-0	270.45 [11]	Ash <0.10%; Water content <0.10%	7.02 [11]
C12-15 alkyl benzoate	68411-27-8	290.44 [11]		7.16 [11]
Hidroxypropyl methylcellulose	9004-65-3	>13000 <200000 [12]		−2.34 [11]
PVM/MA decadiene crosspolymer	136392-67-1	>1000000 [13]	Cyclohexane and ethyl acetate <0.75%; Maleic anhydride negative	n.a.
Cetrimide	1119-97-7	364.45 [11]	Free amines <0.15%; Amine HBr <0.3%; Sulphated ash <0.5%	1.86 [11]
1,5-Pentanediol	111-29-5	104.15		0.58 [14]

∗partition coefficient between n-octanol and water.