Safety Assessment and Biological Effects of a New Cold Processed SilEmulsion for Dermatological Purpose

Table 6

Exposure data of formulation ingredients.

Ingredient	Daily exposure; (mg/kg bw/day)	% in the; final product	Dermal; absorption*	SED; (mg/kg bw/day)
Bis-PEG/PPG-16/16 PEG/PPG-16/16 dimethicone (and) caprylic/capric triglyceride	123.2	5.0	100	6.16
PEG-20 glyceryl laurate	123.2	4.0	100	4.93
Isopropyl myristate	123.2	5.0	100	6.16
C12-15 alkyl benzoate	123.2	5.0	100	6.16
HPMC	123.2	2.0	100	2.46
PVM/MA	123.2	0.3	100	0.37
Cetrimide	123.2	0.075	100	0.09
1,5-Pentanediol	123.2	10.0	100	12.32

∗When no permeation data is available, the value considered is 100%.