Figure 4: Localization of NUMB in odontogenic tissues at postnatal day 3: localization of NUMB in P3 incisors (B) and molars (C and D). NUMB can be detected in the ameloblasts (Am); odontoblasts (Od); ameloblast progenitors (cervical loop); in the dental pulp cells (P) in close vicinity to the odontoblasts. (D1) shows the immature ameloblasts, immature odontoblasts, and dental pulp cells from incisor and molar, respectively. (a) is the negative control. Scale bar represents 100 μm for (a), (c), and (d) and 20 μm for C1 and D1, respectively.