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BioMed Research International
Volume 2013, Article ID 186106, 5 pages
Research Article

Montreal Cognitive Assessment Is Superior to Standardized Mini-Mental Status Exam in Detecting Mild Cognitive Impairment in the Middle-Aged and Elderly Patients with Type 2 Diabetes Mellitus

1Division of Geriatric Medicine, Department of Medicine, University of Alberta, Edmonton, AB, Canada T6G 2G3
2University of Alberta Hospital, B139 Clinical Sciences Building, 8440-112 Street, Edmonton, AB, Canada T6G 2G3
3Department of Medicine, University of Alberta, Edmonton, AB, Canada T6G 2G3
4Division of Endocrinology, Department of Medicine, University of Alberta, Edmonton, AB, Canada T6G 2G3
5School of Public Health, University of Alberta, Edmonton, AB, Canada T6G 2G3

Received 5 April 2013; Revised 19 June 2013; Accepted 19 June 2013

Academic Editor: Kenjiro Ono

Copyright © 2013 Kannayiram Alagiakrishnan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aim. This study compares the usefulness of Montreal Cognitive Assessment (MoCA) to Standardized Mini-Mental Status Exam (SMMSE) for diagnosing mild cognitive impairment (MCI) in Type 2 diabetes mellitus (DM) population. Methods. This prospective pilot study enrolled 30 community dwelling adults with Type 2 DM aged 50 years and above. Subjects were assessed using both the SMMSE and MoCA for MCI. In all subjects, depression and dementia were ruled out using the DSM IV criteria, and a functional assessment was done. MCI was diagnosed using the standard test, the European consortium criteria. Sensitivity and specificity analysis, positive and negative predictive values, likelihood ratios and Kappa statistic were calculated. Results. In comparison to consortium criteria, the sensitivity and specificity of MoCA were 67% and 93% in identifying individuals with MCI, and SMMSE were 13% and 93%, respectively. The positive and negative predictive values for MoCA were 84% and 56%, and for SMMSE were 66% and 51%, respectively. Kappa statistics showed moderate agreement between MoCA and consortium criteria (kappa = 0.4) and a low agreement between SMMSE and consortium criteria (kappa = 0.07). Conclusion. In this pilot study, MoCA appears to be a better screening tool than SMMSE for MCI in the diabetic population.