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BioMed Research International
Volume 2013, Article ID 186439, 8 pages
http://dx.doi.org/10.1155/2013/186439
Research Article

The Use of Continuous Glucose Monitoring Combined with Computer-Based eMPC Algorithm for Tight Glucose Control in Cardiosurgical ICU

Petr Kopecký,1 Miloš Mráz,2 Jan Bláha,1 Jaroslav Lindner,3 Štĕpán Svačina,2 Roman Hovorka,4 and Martin Haluzík2

1Department of Anaesthesia, Resuscitation and Intensive Medicine, 1st Faculty of Medicine and General University Hospital, Charles University in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic
2Third Department of Medicine, 1st Faculty of Medicine and General University Hospital, Charles University in Prague, U Nemocnice 1, 128 08 Prague 2, Czech Republic
3Department of Cardiac Surgery, 1st Faculty of Medicine and General University Hospital, Charles University in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic
4Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Box 289, Cambridge CB2 0QQ, UK

Received 7 September 2012; Revised 19 December 2012; Accepted 20 December 2012

Academic Editor: Sharad Rastogi

Copyright © 2013 Petr Kopecký et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. De Block, B. Manuel-y-Keenoy, P. Rogiers, P. Jorens, and L. Van Gaal, “Glucose control and use of continuous glucose monitoring in the intensive care unit: a critical review,” Current Diabetes Reviews, vol. 4, no. 3, pp. 234–244, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. S. J. Finney, C. Zekveld, A. Elia, and T. W. Evans, “Glucose control and mortality in critically Ill patients,” Journal of the American Medical Association, vol. 290, no. 15, pp. 2041–2047, 2003. View at Publisher · View at Google Scholar · View at Scopus
  3. G. Van Den Berghe, P. Wouters, F. Weekers et al., “Intensive insulin therapy in critically ill patients,” The New England Journal of Medicine, vol. 345, no. 19, pp. 1359–1367, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. J. S. Krinsley, “Effect of an intensive glucose management protocol on the mortality of critically Ill adult patients,” Mayo Clinic Proceedings, vol. 79, no. 8, pp. 992–1000, 2004. View at Google Scholar · View at Scopus
  5. J. C. Preiser, P. Devos, S. Ruiz-Santana et al., “A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study,” Intensive Care Medicine, vol. 35, no. 10, pp. 1738–1748, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Finfer, R. Bellomi, D. Blair et al., “Intensive versus conventional glucose control in critically Ill patients,” The New England Journal of Medicine, vol. 360, no. 13, pp. 1283–1297, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. VISEP, K. Reinhart, T. Deufel, and M. Löffler, “Efficacy of volume substitution and insulin therapy in severe sepsis (VISEP Trial),” ClinicalTrialsgov, NCT00135473, 2003. View at Google Scholar
  8. M. Mraz, P. Kopecky, R. Hovorka, and M. Haluzik, “Intensive insulin therapy in the ICU: the use of computer algorithms,” British Journal of Intensive Care, vol. 18, no. 4, pp. 129–134, 2008. View at Google Scholar · View at Scopus
  9. R. Hovorka, J. Kremen, J. Blaha et al., “Blood glucose control by a model predictive control algorithm with variable sampling rate versus a routine glucose management protocol in cardiac surgery patients: a randomized controlled trial,” Journal of Clinical Endocrinology and Metabolism, vol. 92, no. 8, pp. 2960–2964, 2007. View at Publisher · View at Google Scholar · View at Scopus
  10. F. Chee, T. Fernando, and P. V. Van Heerden, “Closed-loop glucose control in critically ill patients using continuous glucose monitoring system (CGMS) in real time,” IEEE Transactions on Information Technology in Biomedicine, vol. 7, no. 1, pp. 43–53, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. T. Van Herpe, M. Espinoza, N. Haverbeke, B. De Moor, and G. Van den Berghe :, “Glycemia prediction in critically ill patients using an adaptive modeling approach,” Journal of Diabetes Science and Technology, vol. 1, no. 3, pp. 348–356, 2007. View at Google Scholar
  12. U. Holzinger, J. Warszawska, R. Kitzberger et al., “Real-time continuous glucose monitoring in critically Ill patients: a prospective randomized trial,” Diabetes Care, vol. 33, no. 3, pp. 467–472, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. B. Kalmovich, Y. Bar-Dayan, M. Boaz, and J. Wainstein, “Continuous glucose monitoring in patients undergoing cardiac surgery,” Diabetes Technology & Therapeutics, vol. 14, no. 3, pp. 232–238, 2012. View at Publisher · View at Google Scholar
  14. R. Hovorka, V. Canonico, L. J. Chassin et al., “Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes,” Physiological Measurement, vol. 25, no. 4, pp. 905–920, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. W. L. Clarke, D. Cox, L. A. Gonder-Frederick, W. Carter, and S. L. Pohl, “Evaluating clinical accuracy of systems for self-monitoring of blood glucose,” Diabetes Care, vol. 10, no. 5, pp. 622–628, 1987. View at Google Scholar · View at Scopus
  16. P. A. Goldberg, M. D. Siegel, R. R. Russell et al., “Experience with the continuous glucose monitoring system in a medical intensive care unit,” Diabetes Technology and Therapeutics, vol. 6, no. 3, pp. 339–347, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. A. M. Corstjens, J. J. M. Ligtenberg, I. C. C. van der Horst et al., “Accuracy and feasibility of point-of-care and continuous blood glucose analysis in critically ill ICU patients,” Critical Care, vol. 10, no. 5, article R135, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. T. M. Vriesendorp, J. H. Devries, F. Holleman, M. Dzoljic, and J. B. L. Hoekstra, “The use of two continuous glucose sensors during and after surgery,” Diabetes Technology and Therapeutics, vol. 7, no. 2, pp. 315–322, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. C. De Block, Y. K. B. Manuel, L. Van Gaal, and P. Rogiers, “Intensive insulin therapy in the intensive care unit: assessment by continuous glucose monitoring,” Diabetes Care, vol. 29, no. 8, pp. 1750–1756, 2006. View at Publisher · View at Google Scholar · View at Scopus
  20. G. C. Price, K. Stevenson, and T. S. Walsh, “Evaluation of a continuous glucose monitor in an unselected general intensive care population,” Critical Care and Resuscitation, vol. 10, no. 3, pp. 209–216, 2008. View at Google Scholar · View at Scopus
  21. A. Vlkova, P. Dostal, F. Musil, A. Smahelová, Z. Zadak, and V. Cerny, “Blood and tissue glucose level in critically ill patients: a comparison of different methods of measuring interstitial glucose levels,” Intensive Care Medicine, vol. 35, no. 7, p. 1318, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. B. Jacobs, K. Phan, L. Bertheau, G. Dogbey, F. Schwartz, and J. Shubrook, “Continuous glucose monitoring system in a rural intensive care unit: a pilot study evaluating accuracy and acceptance,” Journal of diabetes science and technology, vol. 4, no. 3, pp. 636–644, 2010. View at Google Scholar · View at Scopus
  23. A. Rabiee, R. N. Andreasik, R. Abu-Hamdah et al., “Numerical and clinical accuracy of a continuous glucose monitoring system during intravenous insulin therapy in the surgical and burn intensive care units,” Journal of diabetes science and technology, vol. 3, no. 4, pp. 951–959, 2009. View at Google Scholar · View at Scopus
  24. H. G. Piper, J. L. Alexander, A. Shukla et al., “Real-time continuous glucose monitoring in pediatric patients during and after cardiac surgery,” Pediatrics, vol. 118, no. 3, pp. 1176–1184, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. I. I. Platas, M. T. Lluch, N. P. Almiñana, A. M. Palomo, M. I. Sanz, and X. K. Vidal, “Continuous glucose monitoring in infants of very low birth weight,” Neonatology, vol. 95, no. 3, pp. 217–223, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. B. C. Bridges, C. M. Preissig, K. O. Maher, and M. R. Rigby, “Continuous glucose monitors prove highly accurate in critically ill children,” Critical Care, vol. 14, no. 5, article 176, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. S. E. Siegelaar, T. Barwari, J. Hermanides, W. Stooker, P. H. J. Van Der Voort, and J. H. DeVries, “Accuracy and reliability of continuous glucose monitoring in the intensive care unit: a head-to-head comparison of two subcutaneous glucose sensors in cardiac surgery patients,” Diabetes Care, vol. 34, no. 3, article e31, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. C. Lorencio, Y. Leal, A. Bonet et al., “Real-time continuous glucose monitoring in an intensive care unit: better accuracy in patients with septic shock,” Diabetes Technology & Therapeutics, vol. 14, no. 7, pp. 568–575, 2012. View at Publisher · View at Google Scholar
  29. R. Brunner, R. Kitzberger, W. Miehsler, H. Herkner, C. Madl, and U. Holzinger, “Accuracy and reliability of a subcutaneous continuous glucose-monitoring system in critically ill patients,” Critical Care Medicine, vol. 39, no. 4, pp. 659–664, 2011. View at Publisher · View at Google Scholar · View at Scopus
  30. J. Plank, J. Blaha, J. Cordingley et al., “Multicentric, randomized, controlled trial to evaluate blood glucose control by the model predictive control algorithm versus routine glucose management protocols in intensive care unit patients,” Diabetes Care, vol. 29, no. 2, pp. 271–276, 2006. View at Google Scholar · View at Scopus
  31. C. Pachler, J. Plank, H. Weinhandl et al., “Tight glycaemic control by an automated algorithm with time-variant sampling in medical ICU patients,” Intensive Care Medicine, vol. 34, no. 7, pp. 1224–1230, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. J. Blaha, P. Kopecky, M. Matias et al., “Comparison of three protocols for tight glycemic control in cardiac surgery patients,” Diabetes Care, vol. 32, no. 5, pp. 757–761, 2009. View at Publisher · View at Google Scholar · View at Scopus
  33. D. E. G. Griesdale, R. J. De Souza, R. M. Van Dam et al., “Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data,” CMAJ, vol. 180, no. 8, pp. 821–827, 2009. View at Publisher · View at Google Scholar · View at Scopus
  34. R. Hovorka and J. Cordingley, “Parenteral glucose and glucose control in the critically ill: a kinetic appraisal,” Journal of Diabetes Science and Technology, vol. 1, no. 3, pp. 357–365, 2007. View at Google Scholar