Improving Drug Loading of Mucosal Solvent Cast Films Using a Combination of Hydrophilic Polymers with Amoxicillin and Paracetamol as Model Drugs

Table 3

Mucoadhesion characteristics for film or drug loaded (paracetamol or amoxicillin) films (mean ± SD (𝑛=3)).

Formulation	Stickiness (N)	Work of adhesion (N⋅mm)	Cohesiveness (mm)
CAR : CMC : GLY	40.38 ± 1.6	44.23 ± 3.9	1.64 ± 0.3
SA : CMC : GLY	38.56 ± 0.6	37.09 ± 6.9	1.18 ± 0.3
CAR : CMC : GLY + paracetamol	39.36 ± 0.8	45.04 ± 4.3	1.39 ± 0.2
SA : CMC : GLY + amoxicillin	38.14 ± 0.5	28.57 ± 5.6	0.94 ± 0.3