Role of the eNOS-NO System in Regulating the Antiproteinuric Effects of VEGF Receptor 2 Inhibition in Diabetes

<table>Urine protein excretion in diabetic Ren-2 rats treated with vehicle, vandetanib, or vandetanib + L-NAME for 24 days. <svg height="13.95" id="M30" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.324997 13.95" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus vehicle and   <svg height="16.0875" id="M31" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 73.324997 16.0875" width="73.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus either vehicle or vandetanib. </table>

BioMed Research International

fig4

Figure 4

Figure 4: Role of the eNOS-NO System in Regulating the Antiproteinuric Effects of VEGF Receptor 2 Inhibition in Diabetes 