Research Article
Prediction of Clinically Relevant Safety Signals of Nephrotoxicity through Plasma Metabolite Profiling
Table 1
Sum of toxicity patterns matching phenytoin-induced metabolite changes.
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Tabulation of the number of specific patterns associated with a given toxicity that: (1) have a confirmed match (see Section 2) with the metabolite profile of phenytoin treated animals at either the high or low dose, and (2) matched the metabolite profile of treated animals with a median correlation greater than 0.5 at either dose. Data taken from [25]. |