Research Article
Prognostic Value of Combined Aquaporin 3 and Aquaporin 5 Overexpression in Hepatocellular Carcinoma
Table 3
Multivariate survival analysis of five-year overall and disease-free survival in 130 patients with hepatocellular carcinoma.
| Features | Five-year overall survival | Five-year disease-free survival | HR | 95% CI | P | HR | 95% CI | P |
| Age | 1.132 | 0.316–3.516 | 0.192 | 1.536 | 0.322–3.736 | 0.125 | Gender | 1.191 | 0.345–3.857 | 0.136 | 1.559 | 0.357–3.831 | 0.131 | Serum AFP | 1.931 | 0.685–4.056 | 0.063 | 1.953 | 0.615–4.273 | 0.062 | Tumor stage | 2.879 | 1.366–5.196 | 0.009 | 2.686 | 1.386–6.009 | 0.01 | Tumor grade | 1.563 | 0.609–4.088 | 0.081 | 1.551 | 0.607–4.466 | 0.086 | Presence of cirrhosis | 1.919 | 0.738–4.102 | 0.063 | 1.921 | 0.793–4.219 | 0.062 | AQP3 expression | 5.398 | 1.312–11.338 | 0.01 | 5.200 | 1.343–11.186 | 0.01 | AQP5 expression | 8.476 | 1.993–17.286 | 0.006 | 5.936 | 1.312–12.588 | 0.01 | AQP3/AQP5 expression | 6.982 | 1.601–15.193 | 0.009 | 5.695 | 1.381–11.902 | 0.01 |
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