BioMed Research International / 2013 / Article / Fig 4

Research Article

Modification of a Rodent Hindlimb Model of Secondary Lymphedema: Surgical Radicality versus Radiotherapeutic Ablation

Figure 4

Upregulation of lymphatic specific genes after coculture of MDSCs with the supernatant of HLECs. (a) RT-PCR demonstrates negative expression of genes for Prox-1, FLt-4, and podoplanin in native MDSCs, while the coculture demonstrates upregulation of these genes. (b) Graphical representation of gene expression rate normalized against actin. There is upregulation of genes for Prox-1, FLt-4, and podoplanin after coculture compared to native MDSCs.

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