Research Article

Identification of Interconnected Markers for T-Cell Acute Lymphoblastic Leukemia

Table 2

KEGG and GO enrichments of the most frequent 19 subnetworks.

SubnetworksKEGGGO: function

Sub-1No enrichmentsActin binding, calmodulin binding
Sub-2Chemokine-signaling pathway, Chemokine-cytokine receptor interaction, endocytosisSignal-transducer activity, chemokine activity, and cytokine activity
Sub-3ECM-receptor interaction, focal adhesion, and hematopoietic cell lineage Growth factor binding, extracellular matrix structural constituent
Sub-4Pathways in cancer, colorectal cancer, pancreatic cancer, chronic myeloid leukemia, cell cycle, Wnt signaling pathway, and MAPK signaling pathwayPromoter binding, transcription activator activity, and transcription factor activity
Sub-5Neuroactive ligand-receptor interactionSignal-transducer activity, G-protein coupled receptor activity
Sub-6No enrichmentsNo enrichments
Sub-7No enrichmentsNo enrichments
Sub-8Pathways in cancer, colorectal cancer, and Wnt signaling pathwayNo enrichments
Sub-9Leukocyte transendothelial migration, regulation of actin cytoskeleton, dilated cardiomyopathy, Fc gamma R-mediated phagocytosis, and hypertrophic cardiomyopathy (HCM)GTP binding, actin binding
Sub-10Phagosome, gap junction GTP binding, GTPase activity, nucleotide binding, and structural molecule activity
Sub-11No enrichmentsMetal-ion binding, calcium ion binding, SH3 domain binding, and phospholipid transporter activity
Sub-12No enrichmentsNo enrichments
Sub-13Complement and coagulation cascadesNo enrichments
Sub-14Bladder cancer Calcium ion binding, metalloendopeptidase activity
Sub-15Toll-like receptor signaling pathwayTransmembrane receptor activity
Sub-16Pathways in cancer, neurotrophin signaling pathway, ErbB signaling pathway, and nonhomologous endjoiningATP binding, protein C-terminus binding
Sub-17Toll-like receptor signaling pathway, pathogenic Escherichia coli infectionTransmembrane receptor activity
Sub-18Tight junction, endocytosisNo enrichments
Sub-19No enrichmentsNo enrichments