Identification of Interconnected Markers for T-Cell Acute Lymphoblastic Leukemia

Table 7

Zinc-ion binding proteins recovered in subnetworks.

Gene symbol	Gene title	Subnetwork	Behavior
TP53	Tumor protein p53	Sub-4	Up
ATF2	Activating transcription factor 2	Sub-4	Up
WT1	Wilms, tumor 1	Sub-4	Up
SALL2	Sal-like 2 (Drosophila)	Sub-6	Up
EWSR1	Ewing sarcoma breakpoint region 1	Sub-6, sub-7	Up
USP13	Ubiquitin specific peptidase 13 (isopeptidase T-3)	Sub-8	Up
CXXC4	CXXC finger 4	Sub-8	Up
LASP1	LIM and SH3 protein 1	Sub-9	Down
GFI1B	Growth factor independent 1B transcription repressor	Sub-11	Down
APP	Amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer’s disease)	Sub-13	Down
MEP1A	Meprin A, alpha (PABA peptide hydrolase)	Sub-14	Non-DE
MMP9	Matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, and 92 kDa type IV collagenase)	Sub-14	Down
RASA4	RAS p21 protein activator 4	Sub-16	Up
BTK	Bruton agammaglobulinemia tyrosine kinase	Sub-17	Down
USP20	Ubiquitin specific peptidase 20	Sub-18	Up
PRKCI	Protein kinase C, iota	Sub-18	Up