Exploring Different Virtual Screening Strategies for Acetylcholinesterase Inhibitors

Figure 4

Redocking experiment of donepezil using pdb 1b41. (a) When redocked with a 60 × 60 × 60 grid size, RMSD = 0.69 Å. (b) When redocked with 110 × 110 × 110 grid, RMSD = 4.34 Å.

(a)

(b)