Exploring Different Virtual Screening Strategies for Acetylcholinesterase Inhibitors
Figure 6
Chosen pharmacophoric hypothesis. (a) Overlaid on the binding site of donepezil bound to PDB ID 1eve. (b) The pharmacophore model depicting the inter-pharmacophoric distances. Ligand structure aligned on the pharmacophore model is donepezil. Hydrogen bond acceptor (A), hydrophobe (H), and aromatic ring (R).
