BioMed Research International / 2013 / Article / Fig 4

Research Article

Indomethacin-Enhanced Anticancer Effect of Arsenic Trioxide in A549 Cell Line: Involvement of Apoptosis and Phospho-ERK and p38 MAPK Pathways

Figure 4

The effects of ATO and Indo and their combinations on the expression of COX-2 mRNA. (a) RT-PCR reaction products were resolved on 1% agarose gel and stained with Ethidium bromide. (b) Densitometric analyses of COX-2 mRNA expression is presented as the band’s density to control (β-actin) of three independent experiments (Mean ± SE, ). (c) The effect of Indo alone (light columns) and combination with ATO 2 μM (dark columns) on COX-2 expression.
237543.fig.004a
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237543.fig.004b
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