Association of Genetic Variants of BMP4 with Type 2 Diabetes Mellitus and Clinical Traits in a Chinese Han Population

Table 3

Associations of three haplotypes in BMP4 region with type 2 diabetes.

Haplotype	Haplotype frequencies		P value (empirical P value)
	Cases	Controls
Block1 (rs1951867-rs7146040)
GA	0.805	0.801	0.522
CA	0.097	0.103	0.248
GG	0.097	0.096	0.755
Block2 (rs17563-rs2071047)
TT	0.368	0.355	0.116
TC	0.358	0.361	0.688
CC	0.274	0.284	0.210
Block3 (rs8014071-rs8014363-rs7141785-rs6572927)
ATCA	0.365	0.366	0.960
GTCT	0.348	0.338	0.223
ACCT	0.117	0.127	0.056 (0.4263)
ATTT	0.096	0.098	0.705
ATCT	0.073	0.068	0.247

P values <0.1 were shown in bold.
Empirical P values are for the haplotypes based on 10,000 permutations.