Meta-Analysis of Microarray Data Identifies GAS6 Expression as an Independent Predictor of Poor Survival in Ovarian Cancer
GAS6 is overexpressed in ovarian cancers. (a) Box plot demonstrating GAS6 weighted average expression scores on various ovarian tissues as assessed by immunohistochemistry. Statistical test performed was the Kruskal-Wallis test. OSE: ovarian surface epithelium; CystA: cystadenoma; OBL: ovarian borderline tumour; EOC: epithelial ovarian cancer. (b) Western blots for GAS6 on a panel of ovarian cell lines. Left panel shows original blot, right panel shows relative expression based on densitometric analysis (density of GAS6 divided by density of GAPDH). Results from a representative experiment are shown. Normal cell lines (HOSE6.3 and HOSE17.1) are marked (framed or black bars).