Research Article
What Is the Role of Apelin regarding Cardiovascular Risk and Progression of Renal Disease in Type 2 Diabetic Patients with Diabetic Nephropathy?
Table 2
Comparison of variables among the 3 apelin-36 tertiles.
| | | Group 1
(<98 pg/mL) | Group 2
98–328 (pg/mL) | Group 3
≥329 (pg/mL) | value |
| | Resistin (pg/mL) | 1.0 ± 0.3 | 0.8 ± 0.6 | 0.5 ± 0.3 | <0.001 | | Log visfatin (pg/mL) | 2.1 ± 1.7 | 1.7 ± 1.7 | 1.3 ± 1.4 | <0.001 | | Adiponectin (ng/mL) | 10.8 ± 7.9 | 30.1 ± 16.5 | 45.7 ± 18.7 | <0.001 | | Interleukin-6 (IL-6) (pg/mL) | 8.8 ± 3.0 | 6.4 ± 4.0 | 3.3 ± 1.8 | <0.001 | | Oxidized LDL (OxLDL) (U/L) | 67.3 ± 18.7 | 39.0 ± 19.0 | 30.1 ± 9.1 | <0.001 | | Estimated glomerular filtration rate (eGFR) (mL/min) | 29.7 ± 20.3 | 48.6 ± 21.2 | 49.5 ± 24.1 | <0.001 | | Homeostasis model of assessment: insulin resistance (HOMA-IR) | 3.8 ± 1.3 | 2.1 ± 1.5 | 0.6 ± 0.4 | <0.001 | | Parathyroid hormone (PTH) (pg/mL) | 217.4 ± 135.0 | 120.2 ± 61.4 | 76.3 ± 41.2 | <0.001 | | Phosphorus (mg/dL) | 5.2 ± 1.4 | 4.3 ± 0.8 | 3.6 ± 0.7 | <0.001 | | Albumin/creatinine ratio | 268.9 ± 108.6 | 255.5 ± 123.8 | 209.2 ± 108.7 | 0.026 | | Left ventricular mass index (LVMI) (g/m2) | 133.2 ± 16.2 | 100.5 ± 15.3 | 80.8 ± 9.1 | <0.001 | | Intima-media thickness (IMT) (mm) | 1.2 ± 0.2 | 1.0 ± 0.3 | 0.8 ± 0.1 | <0.001 | | Pulse pressure (PP) (mmHg) | 68.7 ± 13.9 | 47.0 ± 19.3 | 43.1 ± 12.3 | <0.001 |
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