Metabolite Profile Resulting from the Activation/Inactivation of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 2-Methyltetrahydro-β-carboline by Oxidative Enzymes
Figure 5
HPLC chromatograms of metabolites from 2-methyl-1,2,3,4-tetrahydro-β-carboline incubated with cytochrome P450 2D6 (a) and myeloperoxidase (b). Enzyme assays and chromatographic conditions were as indicated in experimental section.
