Clinical Study
A Flow Cytometric Analysis of Vitreous Inflammatory Cells in Patients with Proliferative Diabetic Retinopathy
Table 5
Comparison of samples from the nPDR group and the MH group (median, minimum–maximum; Mann Whitney
test).
| | | Vitreous | Blood | | | nPDR () | MH () | P value | nPDR () | MH () | P value |
| | CD45 (number) | 401.0 (181.0–1644.0) | 132.0 (80.0–429.0) | 0.005 | 107079.5 (100911.0–168812.0) | 109862.5 (100618.0–127659.0) | 0.64 | | Ly (%) | 3.3 (0.4–55.5) | 1.0 (0–2.6) | 0.044 | 30.2 (10.4–82.1) | 23.0 (14.3–63.9) | 0.512 | | CD14all (%) | 64.1 (34.0–79.3) | 52.75 (17.9–83.0) | 0.223 | 6.0 (2.2–12.0) | 8.0 (5.0–21.0) | 0.144 | | CD19 (%) | 0 (0-0) | 0 (0-0) | 0.48 | 8.4 (3.0–83.0) | 8.45 (4.9–19.4) | 0.925 | | CD3 (%) | 57.5 (0–100.0) | 0 (0-0) | 0.025 | 59.9 (12.6–95.6) | 61.1 (36.6–67.0) | 0.453 | | CD3/CD19 | 84.0 (47.7–100.0) | | | 7.5 (3.1–27.0) | 4.6 (2.8–13.3) | 0.454 | | CD4 (%) | 64.0 (0–100.0) | 0 (0-0) | 0.025 | 61.3 (24.7–78.4) | 58.8 (32.0–75.3) | 0.851 | | CD8 (%) | 0 (0–26.0) | 0 (0-0) | 0.075 | 32.3 (16.9–68.2) | 33.4 (21.4–59.4) | 1.0 | | CD4/CD8 | 3.9 (2.2–100.0) | | | 2.05 (0.4–8.2) | 1.8 (1.3–3.5) | 0.963 |
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Legend: nPDR: PDR patients with blood non-contaminated vitreous; MH: patients with macular hole; CD45+: leukocytes; Ly: lymphocytes; CD14+: macrophages; CD19+: B lymphocytes; CD3+: T lymphocytes; CD4+: T helper lymphocytes; CD8+: T cytotoxic lymphocytes.
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