A Flow Cytometric Analysis of Vitreous Inflammatory Cells in Patients with Proliferative Diabetic Retinopathy

Table 6

Comparison of vitreous samples from nPDR group with active and quiescent PDR (median, minimum–maximum; Mann Whitney 𝑈 test).

	nPDR (𝑁=12)
	Active PDR (𝑛=6)	Quiescent PDR (𝑛=6)	P value
CD45 (n)	666.0 (342.0–1644.0)	240.5 (181.0–605.0)	0.055
Ly (%)	17.0 (2.0–55.5)	1.7 (0.4–9.7)	0.025
CD14all (%)	48.8 (34.0–77.0)	66.2 (53.4–79.3)	0.2
CD19 (%)	0 (0–1.0)	0 (0-0)	0.317
CD3 (%)	82.5 (68.0–100.0)	0 (0–47.4)	0.003
CD3/CD19	88.5 (68.0–100.0)
CD4 (%)	73.9 (57.0–100.0)	0 (0–100.0)	0.037
CD8 (%)	20.0 (0–26.0)	0 (0-0)	0.007
CD4/CD8	3.85 (2.2–100.0)

Legend: nPDR: PDR patients with blood non-contaminated vitreous; CD45+: leukocytes; Ly: lymphocytes; CD14+: macrophages; CD19+: B lymphocytes; CD3+: T lymphocytes; CD4+: T helper lymphocytes; CD8+: T cytotoxic lymphocytes.