Research Article

Harmine and Harmaline Downregulate TCDD-Induced Cyp1a1 in the Livers and Lungs of C57BL/6 Mice

Table 1

Representation of different groups of C57BL/6 mice and the dose schedule for each group.

Treatments groupsTime (h)
−40+4+14

Group 1SalineSaline + corn oilSalinesacrifice
Group 2SalineSaline + TCDD (15 μg/kg)Salinesacrifice
Group 3Harmine (10 mg/kg)Harmine (10 mg/kg) + TCDD (15 μg/kg)Harmine (10 mg/kg)sacrifice
Group 4Harmaline (10 mg/kg)Harmaline (10 mg/kg) + TCDD (15 μg/kg)Harmaline (10 mg/kg)sacrifice