Identification of Lung-Cancer-Related Genes with the Shortest Path Approach in a Protein-Protein Interaction Network

Table 2

Overlap between candidate genes and cancer-related genes.

Gene set	Number of candidate genes	Overlap with 742 cancer genes	P value
NSCLC from array	1825	93	6.698𝑒−04
SCLC from array	1063	69	2.218𝑒−06
NSCLC in our study	25	6	2.518𝑒−05
SCLC in our study	38	5	2.559𝑒−03

P value was calculated with the hypergeometric test assuming the total number of protein-coding genes was 20000.