MMP1, MMP9, and COX2 Expressions in Promonocytes Are Induced by Breast Cancer Cells and Correlate with Collagen Degradation, Transformation-Like Morphological Changes in MCF-10A Acini, and Tumor Aggressiveness
Figure 4
Protein levels of cyclooxygenase 2 and prostaglandin E2. Densitometric analysis of the immunocytochemical detection of COX2 (a) and PGE2 (b) in single MDA-MB-231 and U937 or combined cultures of both cells (CC). Bars with asterisks represent comparisons with statistical significance (). (c) Representative images of COX2 and PGE2 levels in MDA-MB-231 and U937 cells after single or combined culture (200x optical magnification).