Tamoxifen Treatment in Hamsters Induces Protection during Taeniosis by Taenia solium
Figure 2
Tamoxifen inhibits the in vitro evagination and development of Taenia solium cysticerci in a time-dependent manner. (a) Time-response curves for evaluating the in vitro effect of tamoxifen on the evagination of T. solium cysticerci after 20 days in culture. (b) Time-response curves for evaluating the effect of tamoxifen on the growth of in vitro differentiated T. solium worms after 20 days in culture. Control = parasites cultured in FCS-free DMEM; Vehicle = parasites cultured in FCS-free DMEM containing 0.06% ethanol. Tamoxifen was dissolved in 0.06% ethanol to the desired stock concentration (Tam). Data were pooled from two independent experiments using cysticerci obtained from two different pigs. Results are presented as mean ± standard deviation. Differences were considered significant when . **Significant differences concerning control groups.
