BioMed Research International / 2013 / Article / Tab 1

Research Article

Characterization of an Antihypertensive Angiotensin I-Converting Enzyme Inhibitory Peptide from the Edible Mushroom Hypsizygus marmoreus

Table 1

Comparison of sequence and ACE inhibitory activity between ACE inhibitory peptides from some mushrooms and Hypsizygus  marmoreus in this study.

MushroomsPeptide Molecular
weight (Da)
IC50(mg/mL)aReferences

Pleurotus cornucopiae RLPSEFDLSAFLRA1622.850.460 Jang et al. 2011 [11]
RLSGQTIEVTSEYLFRH2037.261.140
Pholiota adiposa GOGGP414.000.044Koo et al. 2006 [10]
Tricholoma giganteum GOP301.100.040Lee et al. 2004 [9]
Hypsizygus marmoreus LSMGSASLSP567.300.190This study

Captopril17.9 nMcommercial drug

The concentration of an ACE inhibitor required to inhibit 50% of ACE activity.