A Retrospective Longitudinal Cohort Study of Antihypertensive Drug Use and New-Onset Diabetes in Taiwanese Patients

Table 2

Incidence of odds ratios (ORs) with 95% confidence intervals (CIs) for NOD according to prescriptions for antihypertensive drugs compared with nonuser subjects.

Drugs	Adjusted OR*	Adjusted 95% CI	𝑃^∗∗ value
Thiazide diuretics	1.65	1.12–2.45	0.012
Beta-blockers	1.39	0.94–2.06	0.099
DHP CCB	1.24	0.84–1.82	0.276
Non-DHP CCB	1.96	1.01–3.75	0.044
Alpha-blockers	0.71	0.31–1.68	0.445
ACE inhibitors	1.53	0.90–2.64	0.117
ARBs	1.16	0.77–1.75	0.470
Vasodilators	0.92	0.53–1.60	0.777

*ORs were adjusted for age, sex, current smoking, familial history of DM, BMI, total cholesterol, Triglyceride, LDL cholesterol, HDL cholesterol, and fasting blood sugar.
** 𝑃 value between users and nonusers.
DHP-CCB: dihydropyridine calcium channel blockers.
Non-DHP CCB: nondihydropyridine calcium channel blockers.
ACE: angiotensin converting enzyme.
ARB: angiotensin receptor blocker.