Colon Targeted Guar Gum Compression Coated Tablets of Flurbiprofen: Formulation, Development, and Pharmacokinetics

Table 2

Composition of FLB compression coated tablets.

Formulation code*	FLB core tablet (mg)	Guar gum (mg)	Total tablet weight (mg)
F1	175	20	375
F2	175	40	375
F3	175	60	375
F4	175	80	375
F5	175	100	375
Total thickness	3.68±0.04 mm
Total diameter	10.04±0.02 mm
Coat thickness	0.62±0.05 mm
Coat diameter	3.04±0.01 mm

∗Each compression coat formulation contains 10% HPMC, 1% magnesium stearate, 2% talc, and spray dried lactose to make the compression coat weight 200 mg.