BioMed Research International / 2013 / Article / Tab 4

Clinical Study

Colon Targeted Guar Gum Compression Coated Tablets of Flurbiprofen: Formulation, Development, and Pharmacokinetics

Table 4

Release kinetics of FLB-GG compression coated tablets.

FormulationZero order First orderHiguchi
(mg/hr) (hr−1) (mg/hr−1/2)

F124.590.9601.146890.92044.280.823
F221.330.9780.911990.89844.060.854
F33.3330.9710.175030.80816.700.872
F43.3910.9630.177330.79717.050.872
F51.7980.9480.15660.7559.2460.897

: zero-order rate constant, : first-order rate constant, : higuchi model rate constant, and : correlation coefficient.

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