Research Article

Evaluation of the Toxicity of Pradosia huberi Extract during the Preimplantation in Wistar Rats

Table 2

Body weight and absolute and relative weights of rats treated with the hydroalcoholic extract of P. huberi during the preimplantation.

VariablesHydroalcoholic extract of Pradosia huberi
Control
( )
1.22 mg/kg
( )
6.1 mg/kg
( )
30.5 mg/kg
( )

Body weight (g)252.3 ± 7.2242.1 ± 9.7236.8 ± 7.8248.3 ± 5.5
Absolute weight (mg)
 Hypophysis10.1 ± 0.111.3 ± 0.211.6 ± 0.311.9 ± 0.3
 Right ovary 34.6 ± 0.631.7 ± 0.832.2 ± 1.131.1 ± 0.8
 Left ovary 32.7 ± 0.831.4 ± 0.830.8 ± 0.932.1 ± 0.8
 Uterus 783.6 ± 35.7693.2 ± 39.0690.0 ± 42.1724.9 ± 58.9
Relative weight (%)
 Hypophysis 0.003 ± 0.00010.004 ± 0.0001*0.005 ± 0.0002*0.005 ± 0.0002*
 Right ovary 0.01 ± 0.00040.01 ± 0.00040.01 ± 0.00070.01 ± 0.0004
 Left ovary 0.01 ± 0.00060.01 ± 0.00060.01 ± 0.00060.01 ± 0.0004
 Uterus 0.30 ± 0.0020.24 ± 0.0020.25 ± 0.0030.26 ± 0.002

Values are mean ± S.E.M. * versus control.