The Vitamin D Receptor (VDR) Gene Polymorphisms in Turkish Brain Cancer Patients

Table 2

Genotype and allele frequencies of meningioma cases, glioma cases, and controls.

SNP	Controls 𝑛 (%); (𝑛=122)	Meningioma 𝑛 (%); (𝑛=44)	𝜒^2	𝑃 value	Glioma 𝑛 (%); (𝑛=56)	𝜒^2	𝑃 value
*Fok-I genotype
FF	56 (45.9%)	19 (43.2%)			28 (50.0%)
Ff	63 (51.6%)	18 (40.9%)	10.527	0.005	23 (41.1%)	4.598	0.1
ff	3 (2.5%)	7 (15.9%)			5 (8.9%)
*Fok-1 alleles
F	175 (71.7%)	56 (63.6%)			79 (70.5%)
f	69 (28.3%)	32 (36.4%)	1.997	0.157	33 (29.5%)	0.052	0.818
^#Taq-I genotype
TT	65 (53.3%)	23 (52.3%)			32 (57.1%)
Tt	44 (36.0%)	18 (40.9%)	0.703	0.704	18 (32.2%)	0.275	0.872
tt	13 (10.7%)	3 (6.8%)			6 (10.7%)
^#Taq-I alleles
T	174 (71.3%)	64 (72.7%)			82 (73.2%)
t	70 (28.7%)	24 (27.3%)	0.064	0.800	30 (26.8%)	0.137	0.710

Chi-square test was used to compare alleles and clinic pathological characteristics in the study group. 𝑛: number of individuals.
*For Fok 1 polymorphism (rs2228570): F is referred to as T allele, and f is referred to as C allele.
^#For Taq 1 polymorphism (rs731236): T is referred to as T allele, and t is referred to as C allele.
Due to the same base changes T-C or C-T for both polymorphisms, it should be shown as the initial letter of the polymorphism.