Stat3 Upregulates Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 4 Expression in Osteosarcoma Cells

Figure 3

Stat3 knockdown results in a reduction of LGR4 expression. (a–d) mRNA and protein levels of LGR4 were analyzed by Real-time PCR (a, c) and Western blot (b, d) in MG63 or U2OS cells transfected with siRNA oligos targeting Stat3 or negative controls (NC) for 24 or 36 hr, respectively. ^∗𝑃<0.05; ^∗∗𝑃<0.01; ^∗∗∗𝑃<0.001.

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