BioMed Research International / 2013 / Article / Tab 5

Research Article

Role of the Promoter Polymorphism IL-6 −174G/C in Dermatomyositis and Systemic Lupus Erythematosus

Table 5

Comparison between the genotypes and DM clinical parameters.

GenotypeGG ( )GC ( )CC ( ) value

Muscle weakness12 (85.7%)11 (100.0%)5 (50.0%)GG + GC—P = 0.012, G—P = 0.023
Elevated muscle enzymes8 (57.1%)9 (81.8%)2 (20.0%)GG + GC—P = 0.013, G—P = 0.054
EMG findings7 (50.0%)8 (72.7%)5 (50.0%) NS*
Cutaneous disease11 (78.6%)9 (81.8%)7 (70.0%)NS
Photosensitivity10 (71.4%)6 (54.5%)5 (50.0%)NS
Immunological disease (anti-myositis-specific antibodies)3 (21.4%)
4 (36.4%)
2 (20.0%)
NS

Not significant.

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