Further Evidence of Mutational Heterogeneity of the XPC Gene in Tunisian Families: A Spectrum of Private and Ethnic Specific Mutations

Table 3

Clinical features of the XP-C patients.

Patients code	Sex	Age at first consultation; (years)	Age; (years)	City geographic; origin	Age at onset of the first skin tumor; (years) (number)			Internal cancer (age at onset)	Protection from UVR
					MM	BCC	SCC
XP16KEB	M	2	7	Kebelli	—	—	—	—	+++
XP28SFA	F	3	21	Sfax	—	17 (1)	—	Benign articular tumor of the knee (18)	+++
XP45GB	F	2	18	Gafsa	17 (1)	8 (>20)	9 (>10)	Thyroid cancer (16)	+
XP50NEF	M	6	22	Nefta	17 (1)	11 (>5)	17 (1)	—	+

MM: melanoma; BCC: Basal Cell Carcinoma; SCC: Spino Cell Carcinoma; +++: high protection; +: low protection.