Figure 2: Clinical assessment of experimental arthritis. (a) Clinical score was evaluated based on erythema and swelling in each paw on a scale of 0–3, giving a maximum score of 6 per mouse. (b) Paw thickness was measured on both rear paws and was added to obtain an average measure for each mouse; the measures were taken seven days after HAO challenge. Statistical analysis, two-way ANOVA, * .