Response of C2C12 Myoblasts to Hypoxia: The Relative Roles of Glucose and Oxygen in Adaptive Cellular Metabolism
The depletion of oxygen within BD biosensor system containing C2C12 cells over a 6-hour culture period. The figures compare culture in low glucose (LG), medium glucose (MG), and high glucose (HG). The results are shown for 200 μL cell samples of cells/mL (♦), cells/mL (□), and cells/mL cultured with the appropriate medium exposed in normoxic ((a)–(c)) and hypoxic ((d)–(f)) environments. Each point represents the mean and standard deviation of six replicates.