State-of-the-Art Fusion-Finder Algorithms Sensitivity and Specificity

Table 1

Filtering steps embedded in the algorithms.

Filters	Fusion finders
	FF	THF	MS	FM	FH	DF	BF	CS
Pair distance	X					X	X	X
Anchor length		X			X			X
Read-through	X	X		X	X		X
Junction-spanning				X	X		X
PCR artifact				X	X		X
Homology	X	X					X
Quality			X	X

FF: FusionFinder; THF: TopHat-fusion; MS: MapSplice; FM: FusionMap; FH: FusionHunter; DF: deFuse; BF: Bellerophontes; CS: ChimeraScan.