Regulation of PKC Autophosphorylation by Calponin in Contractile Vascular Smooth Muscle Tissue

Figure 4

CaP knockdown in aorta dVSM inhibits phosphorylation of PKC𝛼, PKC𝜀. (a) Densitometric analysis of calponin protein levels after knockdown. (b) Decreased phosphorylation of PKC𝛼 in the presence of PE (10 μM) with CaP knockdown. (c) Decreased phosphorylation of PKC𝜀 in the presence of PE (10 μM) with CaP knockdown. Data are mean ± SE; 𝑛=4–7 animals. *𝑃<0.05 and **𝑃<0.01 compared with sham control.

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