Adhesion, Growth, and Maturation of Vascular Smooth Muscle Cells on Low-Density Polyethylene Grafted with Bioactive Substances

Table 3

Cell population doubling time (hours) of rat aortic smooth muscle cells from day 1 to 2, day 2 to 5, and day 5 to 7 after seeding on nonmodified LDPE (pristine), LDPE irradiated with plasma (plasma), LDPE irradiated with plasma and grafted with glycine (Gly), polyethyleneglycol (PEG), bovine serum albumin (BSA), colloidal carbon particles (C), bovine serum albumin and C (BSA+C), and polystyrene dishes (PS dish).

Material/time interval	Pristine	Plasma	Gly	PEG	BSA	C	BSA+C	PS dish
Days 1-2	14.1	32.0	25.0	22.5	33.8	17.7	46.1	59.0
Days 2–5	25.5	13.6	11.3	9.4	11.0	15.7	10.8	11.2
Days 5–7	−21.8*	60.3	−33.6*	−45.5*	−32.1*	−66.9*	−21.9*	33.0

∗Nonproliferating cells.