BioMed Research International / 2013 / Article / Tab 1

Research Article

Paired Ductal Carcinoma In Situ and Invasive Breast Cancer Lesions in the D-Loop of the Mitochondrial Genome Indicate a Cancerization Field Effect

Table 1

Clinical, pathological information with parallel mutation sites in common between both DCIS and IBC for each patient, inclusive of all patient tissue samples. Heteroplasmic sites are scored as mutations.

Patient Age Sample Est Pro HER2 GradeNG TF MS BR EIC Parallel mutations Haplotype

33 65 Mast +3 3 2 3 8 + 192, 224, 304, 311 U5a

36 67 Lump + 1 1 1 1 3 188, 189, 223, 224, 270, 291, 311, 319, 362, 390H

43 51 Biopsy 2 93, 189, 298 V
52Lump++ 22226

46 66 Biopsy + 2 2 3 1 6 126, 189, 223, 291, 357, 362, 390 J

57 41 Lump + + 3 2 3 3 8 + 189, 291, 390 H

64 51 Biopsy182, 183, 249 H
51Mast+ 3 3 3 3 9

74 39 Biopsy + 203, 304 K
40Mast2 3 2 1 6 +

83 49 Lump + 2 2 3 1 6 189 H

89 41 Lump 3 3 3 3 9 189, 223, 224, 291, 298, 311, 362, 390 K

94 50 Lump + + 1 2 2 1 5 93, 189, 224, 291, 311 H

Unavailable information is left blank. NG: nuclear grade; MS: mitotic score; BR: modified Bloom-Richardson grade; EIC: extensive intraductal component.

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