Improvements in the Quantitative Assessment of Cerebral Blood Volume and Flow with the Removal of Vessel Voxels from MR Perfusion Images

Table 3

CBV, CBF, and MTT measured from normal brain parenchyma of the 30 patients.

Removal	CBV (mL/100 g)	sSVD		cSVD
		CBF (mL/100 g/min)	MTT (sec)	CBF (mL/100 g/min)	MTT (sec)
None	4.95 ± 0.87	55.3 ± 9.5	6.39 ± 0.70	52.3 ± 8.3	6.04 ± 0.45
CSF	4.81 ± 0.73	56.4 ± 8.6	5.60 ± 0.61*	53.0 ± 6.9	5.42 ± 0.34*
Vessel	3.09 ± 0.24*	36.4 ± 3.7*	6.32 ± 0.67	36.1 ± 2.8*	5.86 ± 0.44
Both	3.11 ± 0.22*	38.7 ± 3.8*	5.49 ± 0.57*	38.0 ± 2.5*	5.21 ± 0.31*

All data are expressed as the means ± standard deviations.
∗Significant difference between the original data and data after CSF removal, after vessel removal, and after removal of both (^∗𝑃<0.001 from the Mann-Whitney 𝑈 test).