Enzymes Inhibition and Antidiabetic Effect of Isolated Constituents from Dillenia indica

Table 3

Antidiabetic effect of isolated phytoconstituents in STZ-NIC induced diabetic mice.

Groups/treatment	Blood glucose level (mg/dL)
	0 h	4 h	8 h	24 h
(I) Vehicle	85.5±3.2	85.94±2.73	86.2±2.4	85.26±1.77
(II) STZ-NIC	237.23±3.83	239.24±4.32	239.83±5.86	241.87±4.44^a
(III) STZ-NIC + quercetin	204.34±5.56	173.5±5.25^∗	162.23±3.57^∗	165.53±5.57^∗
(IV) STZ-NIC + β-sitosterol	225.68±3.78	142.34±3.4^∗	139.5±3.7^∗	140.27±3.57^∗
(V) STZ-NIC + stigmasterol	207.93±2.85	158.69±3.84	147.25±4.31^∗	148.38±3.72^∗
(VI) STZ-NIC + std.	224.37±4.37	151.37±2.43^∗	128.47±3.72^∗	121.25±5.1^∗

Data represent means ± SEM. ^∗𝑃<0.05 when groups (III) to (VI) are compared with diabetic control, that is, group (II). Std.: standard drug (glibenclamide). ^a𝑃<0.05, when group (II) is compared with group (I).