Research Article
Release of a Wound-Healing Agent from PLGA Microspheres in a Thermosensitive Gel
Table 1
KSL-W/PLGA microspheres: composition of formulations and manufacturing parameters.
| | Formulation | PLGA
(mg) | (CH2Cl2)
(mL) | KSL-W
(mg) | KSL-W
Solvent | PVA %
(w/v) | Stirring
(°C) Time |
| | A | 600 | 20 | 200 | 2 mL DIW*
0.1 mL Tween 20 | 0.35 | 25°C 30 m
40°C 1 hr | | B | 600 | 20 | 200 | 4 mL DIW + 0.1 mL Tween 20 | 0.35 | 25°C 30 m
40°C 1 hr | | C | 600 | 20 | 200 | 3 mL DIW + 0.1 mL Tween 20 | 0.35 | 25°C 30 m
40°C 1 hr |
|
|
DIW: deionized water.
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