IRS1, TCF7L2, ADRB1, PPARG, and HHEX Polymorphisms Associated with Atherogenic Risk in Mexican Population

Table 5

Association of polymorphism ADRB1 rs1801253 with atherogenic index.

SNP	Medium risk AI	P	High risk AI	P
	ORa (CI)		ORa (CI)
C/G	1.08 (0.83, 1.41)	0.55	2.94 (1.64, 5.24)	<0.0001*
G/G	2.19 (0.81, 5.95)	0.12	3.40 (0.39, 29.61)	0.27
^dC/G + G/G	1.12 (0.87, 1.46)	0.36	2.96 (1.67, 5.25)	<0.0001*
^rG/G	2.16 (0.79, 5.84)	0.13	2.47 (0.29, 21.27)	0.40
Log additive	1.16 (0.91, 1.47)	0.22	2.52 (1.54, 4.15)	<0.0001*

Adjusted for age, sex, BMI, Disease status, and ancestry percentage. IA Low risk was the Reference category. *Bonferroni corrected P value threshold 𝑃≤0.025. ^dDominant model. ^rRecessive model.
Bold text denotes significant P values (<0.05).